1. Approaching the Asymptote: 20 Years Later
Ruslan Medzhitov 
Immunity 
Volume 30, Issue 6, Pages (June 2009)
DOI: /j.immuni
Copyright © 2009 Elsevier Inc. Terms and Conditions

2. Figure 1 Pattern Recognition Receptors
Major classes of mammalian pattern recognition receptors and some of their representative microbial ligands are shown. Secreted pattern recognition molecules activate complement and function as opsonins. Transmembrane and intracellular receptors trigger signaling pathways for innate host defense and activate adaptive immune responses. Mechanisms of inflammasome activation are still being defined. NLRs, NOD-like receptors; CRD, carbohydrate recognition domain; ITAM, immunoreceptor tyrosine-based activation motif.
Immunity  , DOI: ( /j.immuni )
Copyright © 2009 Elsevier Inc. Terms and Conditions