1. Heart Rate, HF Admissions, and Readmissions

3. Overview

4. Burden of HF and Need for Reduction in Rehospitalizations

5. Cost of HF to Society

6. Challenge of Incorporating New Guideline Suggestions Into Practice

7. Role of Heart Rate as a CV Risk Biomarker

8. Role of Heart Rate as a CV Risk Factor

11. Effect of Ivabradine on Outcomes

12. SHIFT: Efficacy Summary

13. SHIFT: Ivabradine Improves QoL in Patients With HF

14. SHIFT: Heart Rate Reduction and β-Blocker Use

15. Initiation of Heart Rate-Lowering Therapy

16. Patient Selection: When to Consider Ivabradine

17. Ivabradine: Practical Considerations

18. Heart Rate Reduction: What to Expect in Patients With AF

19. What to Expect in Patients With High BP

20. What to Expect in Patients on Digoxin

21. What to Expect in HFpEF

22. Reducing the Cost of HF Therapy

23. Abbreviations

24. Abbreviations (cont)