1. RNA-Directed DNA Methylation: Getting a Grip on Mechanism
Judith Bender 
Current Biology 
Volume 22, Issue 10, Pages R400-R401 (May 2012)
DOI: /j.cub
Copyright © 2012 Elsevier Ltd Terms and Conditions

2. Figure 1 A mechanistic model for RNA-dependent DNA methylation.
RNA-dependent DNA methylation requires transcription through the target region, mediated in plants by Pol V. DMS3, DMS11, and perhaps a partner protein (?) could form a ring that promotes Pol V processivity by gripping together the RNA transcript and template DNA. Asterisks mark potential targets for base pairing with a small RNA protein complex.
Current Biology  , R400-R401DOI: ( /j.cub )
Copyright © 2012 Elsevier Ltd Terms and Conditions