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Volume 123, Issue 6, Pages 1812-1822 (December 2002)
Influence of HIV infection on the response to interferon therapy and the long-term outcome of chronic hepatitis B Vincent di Martino, Thierry Thevenot, Jean–François Colin, Nathalie Boyer, Michèle Martinot, Françoise Degos, Jean–Pierre Coulaud, Jean–Louis Vilde, François Vachon, Claude Degott, Dominique Valla, Patrick Marcellin Gastroenterology Volume 123, Issue 6, Pages (December 2002) DOI: /gast Copyright © 2002 American Gastroenterological Association Terms and Conditions
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Fig. 1 Effect of IFN-α therapy and HIV coinfection on HBe seroconversion rate. (A) HIV-negative IFN-α–treated patients. (B) HIV-positive IFN-α–untreated patients. (C) HIV-negative IFN-α–untreated patients. (D) HIV-positive IFN-α–treated patients. Results of the log-rank tests: A vs. B, P = 0.037; A vs. C, P = 0.012; A vs. D, P = 0.058; B vs. C, P = 0.38; B vs. D, NS; C vs. D, NS. This figure shows that the beneficial effect of IFN-α therapy on long-term HBe seroconversion is only effective in HIV-negative patients. Gastroenterology , DOI: ( /gast ) Copyright © 2002 American Gastroenterological Association Terms and Conditions
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Fig. 2 Comparison of HBV reactivation rates in HIV-positive and HIV-negative patients. Gastroenterology , DOI: ( /gast ) Copyright © 2002 American Gastroenterological Association Terms and Conditions
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Fig. 3 Estimated occurrence of cirrhosis according to HIV status and CD4 cell count. Gastroenterology , DOI: ( /gast ) Copyright © 2002 American Gastroenterological Association Terms and Conditions
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