1. Testing for von Willebrand Disease
Supplemental Data Figure 1.
Testing for von Willebrand Disease
Less then 10% or absent
Factor VIII:C
vWF:Ag
vWF:RCo <10% vWF:CBA <10% Multimerics: loss of all
Type III
Normal (?)
No further testing
Decreased
vWF:RCo Decreased
Multimerics Analysis
Probable Type I
Normal
vWF:CBA
Relative decrease or loss of HWM
vWF:CBA
Normal
Decreased
Normal
Decreased
Multimerics: smeary pattern
Multimerics: loss of HWM
Probable Type I
Probable Type II
Likely Type IIM
Likely Type IIA or IIB