1. 11/16/2018
In Vitro Experiments and Redesign of Distal Protection Filters Used in Carotid Angioplasty Erdrin Azemi Heather Gray Emily Miner AGM Inc. Project Advisor: Ender A. Finol, Ph.D. Project Director: Mark H. Wholey, M.D. Senior Design BioE1160
Heather slide

2. Project Goals/Progress
11/16/2018
Project Goals/Progress
To test four current endovascular filters on the market: (Angioguard TM, Acunet TM, EPI Filter WireTM, and Neuroshield TM)
Currently we are performing preliminary tests to determine a repetitive testing set up
We have all the equipment necessary to perform experiments
Heather Slide
For those of you who do not remember Distal Protection filters are used during angioplasty surgery to protect the patient from stroke. The filter catches any plaque that becomes lose during the angioplasty procedure.

3. Project Goals/Progress
11/16/2018
Project Goals/Progress
To redesign a more effective and efficient endovascular filter protection device
We have yet to start the redesigning process, this all depends on the results of the experiments
If the experiments do not finish in time then we would proceed on the redesign based on literature results
Heather Slide

4. Project Goals/Progress
11/16/2018
Project Goals/Progress
To accomplish all the testing experiments by the end of January
This has not been feasible so far
We have not set an end date for the experiments due to several problems we have encountered with the testing design and setup
Heather Slide

5. Technology Experimentation
11/16/2018
Technology
Experimentation
We will be using a in-vitro flow loop provided by Carnegie Mellon University
 We have set up the in-vitro flow loop
Heather Slide

6. 11/16/2018
Flow Loop
Emily

7. Schematic of Flow Loop Pump and Controller Hemostatic Valve
11/16/2018
Schematic of Flow Loop
Pump and Controller
Hemostatic Valve
Pressure Reader
Reservoir
Flow Reader
Insertion of Filter A
Emily
Split Point B
Injection Point of Particles
Reservoir

8. 11/16/2018
Filters
Emily

9. Schedule Spring 2004 Perform experiments and achieve data ?
11/16/2018
Schedule
Spring 2004
Perform experiments and achieve data ?
Meet with advisors
Write survey and send to physicians
Filter Redesign ?
Design Implementation ?
Final Paper and Presentation ?
Emily
Future plans in spring 2004 include
These are our major milestones for the spring semester.
- Finish up all of the experiment and achieve the necessary data
Meet with Dr. Wholey in the presence of Dr. Finol so we can report our findings (end of Jan)
After all the collected data, we should start thinking about filter redisign and perform a FMEA and HFE
Design Implementation will consist of several meetings with a coworker of Prof Gartner and our advisors
And soon enough we should be able to start working on a solid works model and a design prototype
- By the end of the spring semester we should be able to write a final paper and present our final work.

10. Summary of Successes 1. Flow loop design and setup complete
11/16/2018
Summary of Successes
1.      Flow loop design and setup complete
2.    Methods developed
3.      Experiments started
Wrote survey to send out to physicians
5. Rough draft of paper completed
Erdrin

11. 11/16/2018
Summary of Problems
1.     Quantification of efficiency of filters during experiment
2.      Time line of the experiment /redesign
3. Orders not arriving on time
Absence of Dr. Wholey
Erdrin

12. Team Chores Erdrin A. Heather G. Emily M. Further Literature Research
11/16/2018
Team Chores
Erdrin A.
Heather G.
Emily M.
Further Literature Research
Set up group meetings
Contact advisors
Monitor experiment
Take pictures during experiments
Collect data during experiments
Solid Works Modeling
Write FMEA for redesign
Write HFE for redesign
Fax questionnaire to physicians
Write-up questionnaire
Sort and tally questionnaire results
Put together final presentation
Put together final paper
Erdrin
 The words in orange are the chores that are not yet completed
Although we have set chores for each member of the group, in any case someone can always contribute to help the
Other member such that the project flows

13. Acknowledgements Thank You: Mark Wholey, MD Ender Finol, PhD
11/16/2018
Acknowledgements
Thank You:
Mark Wholey, MD
Ender Finol, PhD
Christine Scotti
Mark Gartner
Bioengineering Department, University of Pittsburgh
Carnegie Mellon University
Erdrin
We would like to thank:
Dr. Wholey for his guidance, his support, and his help in funding this project
Dr. Ender Finol for his patience, his advice and his overall help in every step of our project so far
Mark Gartner for helping us find this project and for providing his own help in this project so we could succeed
The bioe dept at the univ. of Pitt for funding this project
And Elena diMartino for helping set up meetings to further the happening of this project
We would also like to thank CMU for the use of their facilities

14. THANK YOU! ?