1. Drugs acting on Nervous system
Hyoscyamus

2. Monograph of the CNS Drug
Objectives
On completion of this period you would be able to learn about the
Monograph of the CNS Drug
HYOSCYAMUS

3. Known to Unknown Have you seen Datura plant in your collage campus?
To which family it belongs to ?
Can you give other example of Solanaceae drug?
Does Hyoscyamus belongs to Solanaceae ?

4. Syn: Henbane HYOSCYAMUS Biological Source:
It consists of dried leaves or
flowering tops of
Hyoscyamus niger
Family : Solanaceae
Geographical Source:
It is a native of West Asia,
North Africa, Europe and India.
Also cultivated in Russia, Belgium
and Hungary
Fig.29.1

5. Cultivation And Collection
Done in temperate at an altitude of m
Seeds are sown in small seed beds and seedling are raised
Seedlings are transplanted in fields in May by keeping a distance of half meter
Leaves are collected when the plant is flowering
Leaves are carefully dried

6. Morphological Characters
LEAF
Size : Length – 25cm
Shape : Ovate
Apex : Acute
Base : Symmetrical
Fig.29.2

7. Morphological Characters
LEAF
Margin : Triangularly dentate
Surface : Hairy
Colour : Pale greyish green
Odour : Characteristic & strong odour
Taste : Acrid
Fig.29.3

8. Chemical Constituents
Total alkaloidal content is %
In which 75% is Hyoscyamine
Atropine and Hyoscine are present in small amounts

9. Uses Antispasmodic and Antiasthmatic
Used to relieve spasm of urinary tract
Administered with strong Purgatives to prevent gripping
Has weak Parasympatholytic action
Sedative and used to check Salivary secretion

10. Allied Drugs Hyoscyamus albus Grown in France and India
Hyoscyamus muticus
Grown in Egypt and India

11. Summary In this class we discussed about CNS plant drug – HYOSCYAMUS
Its Biological Source, Morphology, Chemical
Constituents, uses and allied drugs

12. Quiz 1. The chief chemical constituents present in Hyoscyamus are
a) Alkaloids
b) Glycosides
c) Latex
d) None of the above

13. Quiz Hyoscyamus belongs to the family a) Annonaceae b) Leguminosae
c) Solanaceae
d) None of the above

14. Frequently Asked Questions
Write the Botanical source and uses of Hyoscyamus
2. Write the Morphological characters and Chemical
Constituents of Hyoscyamus