1. Sima Setayeshgar Theoretical Biophysics
Research Group:
Jianfeng Lv (G)
Xianfeng Song (G)
Lin Wang (G)
Yang Yang (G)

2. What we do… Pattern formation in nonequilibrium systems:
Nonlinear waves in excitable systems with
application to the heart
macroscopic
Physical principles governing design of
biochemical signaling networks:
Noise, robustness, information processing
Synergistic activities (w/ IUB biologists/chemists):
Cell morphology and optimal strategy in
nutrient uptake (Brun lab)
Microbial biofilms (Brun, Fuqua, Jacobsen labs)
cellular
Methodology:
Statistical mechanics, applied mathematics, scientific computing

3. Biochemical Signal Processing
“Counting” molecules by biological receptors, which in turn control downstream events, is a generic task.
Accuracy of measurement is governed by the physics of diffusion.
Theory and experiment indicate that in many cases, performance of cells approaches lower bound set by diffusive counting noise!