1. Roles of Transforming Growth Factor-β in Graft-versus-Host and Graft-versus-Tumor Effects 
Cédric Carli, Martin Giroux, Jean-Sébastien Delisle 
Biology of Blood and Marrow Transplantation 
Volume 18, Issue 9, Pages (September 2012)
DOI: /j.bbmt
Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

2. Figure 1
The multiple effects of TGF-β in GVHD pathophysiology. Graphic summary of acute and chronic GVHD pathogenesis highlighting the influence of TGF-β at multiple key steps. Green circles represent the anti-GVHD properties of TGF-β, and red triangles represent the effects of TGF-β contributing to GVHD development or end-organ damage. Question marks (?) represent important properties of TGF-β in T cell differentiation that have yet to be implicated as TGF-β–related in GVHD pathophysiology. LPS, lipopolysaccharide; iDC, immature dendritic cells; mDC, mature dendritic cells; ROS, reactive oxygen species.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt )
Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions