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A Phase II Study of Tg4010 (Mva-Muc1-Il2) in Association with Chemotherapy in Patients with Stage III/IV Non-small Cell Lung Cancer  Rodryg Ramlau, MD,

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Presentation on theme: "A Phase II Study of Tg4010 (Mva-Muc1-Il2) in Association with Chemotherapy in Patients with Stage III/IV Non-small Cell Lung Cancer  Rodryg Ramlau, MD,"— Presentation transcript:

1 A Phase II Study of Tg4010 (Mva-Muc1-Il2) in Association with Chemotherapy in Patients with Stage III/IV Non-small Cell Lung Cancer  Rodryg Ramlau, MD, PhD, Elisabeth Quoix, MD, PhD, Janusz Rolski, MD, PhD, Miklos Pless, MD, Herve Lena, MD, Eric Lévy, MD, Maciej Krzakowski, MD, PhD, Dagmar Hess, MD, Eric Tartour, MD, Marie-Pierre Chenard, MD, Jean-Marc Limacher, MD, MSc, Nadine Bizouarne, PhD, Bruce Acres, PhD, Céline Halluard, PhD, Thierry Velu, MD  Journal of Thoracic Oncology  Volume 3, Issue 7, Pages (July 2008) DOI: /JTO.0b013e31817c6b4f Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Time to Progression for the whole study period (ITT).
Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31817c6b4f) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Overall Survival (ITT).
Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31817c6b4f) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 TTP and OS according to cellular immune response against MUC1 for the whole study population. Patients with (——–) or without (——) MUC1-specific ELISpot at any timepoint. A: Time to progression. B: Overall survival. o = complete data, + = censored. Differences between the 2 populations are statistically significant with A: p = and B: p = Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31817c6b4f) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions


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