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Bone Marrow Mesenchymal Stem Cell (BM-MSC) Release Microvesicles/Exosomes That Incorporate Into Hematopoietic Cells From MDS Patients and May Modify Their.

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Presentation on theme: "Bone Marrow Mesenchymal Stem Cell (BM-MSC) Release Microvesicles/Exosomes That Incorporate Into Hematopoietic Cells From MDS Patients and May Modify Their."— Presentation transcript:

1 Bone Marrow Mesenchymal Stem Cell (BM-MSC) Release Microvesicles/Exosomes That Incorporate Into Hematopoietic Cells From MDS Patients and May Modify Their Behaviour by Sandra Muntión, Post Doc Fellowship, Teresa Ramos, Bruno Paiva, Beatriz Roson, Maria Eugenia Sarasquete, Maria Diez-Campelo, Maria Teresa Rejas, Marcos González, Jesus F San Miguel, and Maria-Consuelo del Cañizo Blood Volume 122(21): November 15, 2013 ©2013 by American Society of Hematology

2 MVs from MSC -MDS analysed by TEM. A.
MVs from MSC -MDS analysed by TEM. A. Scale bar 500nm. B. Scale bar 200nm Sandra Muntión et al. Blood 2013;122:863 ©2013 by American Society of Hematology

3 CM images A- C Sequential images of CD34+ cells with MVs from MSC-MDS.
CM images A- C Sequential images of CD34+ cells with MVs from MSC-MDS. A. overlay (CD90 in red and CD45 in green), B CD34+ with anti CD 90 (red) and C with anti-CD45 (green). DAPI (blue)‏ Sandra Muntión et al. Blood 2013;122:863 ©2013 by American Society of Hematology


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