1. Research Project Grant (RPG) Retreat R-series
March 2012
Bioengineering Classroom

2. Project Title
To be submitted to [agency] as [R01 or type] on [date]-[new or amended]-responding to [PA or RFA]
Presenter Name
Rank and Affiliation
Total Presentation Time is 20 minutes
Example of a cover slide

3. Specific Aims
State concisely the goals of the proposed research and summarize the expected outcome(s), including the impact that the results of the proposed research will exert on the research field(s) involved
List succinctly the specific objectives of the research proposed
test a stated hypothesis
create a novel design, solve a specific problem, challenge an existing paradigm or clinical practice, address a critical barrier to progress in the field, or develop new technology

4. Specific Aims Example Specific aims (e.g., 1 slide per aim)
A typical number of aims in an R01 is three. Use an outline format for each specific aim
State Specific Aim 1 – “Validate the X system as a model for….”
Briefly state your predictions/actions for each aim.
SA [first sub-Aim: “Our hypothesis predicts that…” or “we will demonstrate that….]
SA [second sub-Aim]
Repeat for each Aim and sub-Aim

5. Research Strategy: Significance
Explain the importance of the problem or critical barrier to progress in the field that the proposed project addresses
Explain how the proposed project will improve scientific knowledge, technical capability, and/or clinical practice in one or more broad fields
Describe how the concepts, methods, technologies, treatments, services, or preventive interventions that drive this field will be changed if the proposed aims are achieved

6. Research Strategy: Innovation
Explain how the application challenges and seeks to shift current research or clinical practice paradigms
Describe any novel theoretical concepts, approaches or methodologies, instrumentation or interventions to be developed or used, and any advantage over existing methods, instruments, or interventions

7. Research Strategy: Approach
Describe the overall strategy, methodology, and analyses to be used to accomplish the specific aims of the project
Discuss potential problems, alternative strategies, and benchmarks for success anticipated to achieve the aims
If the project is in the early stages of development, describe any strategy to establish feasibility, and address the management of any high risk aspects of the proposed work
Provide a tentative sequence or timetable for the project
Up to 3 slides for this portion of the presentation
Include Preliminary Studies if this is a new proposal. Provide an account of any preliminary studies done by the PD/PI that are relevant.

8. Summary
Summarize your presentation
Results/Outcomes
Acknowledgements

9. Competing Renewal Re-submission
Additional Slides
Competing Renewal
Re-submission

10. Competing Renewal (if applicable)
Summarize the previous application’s specific aims and the importance of the findings
Provide a succinct account of published and unpublished results, indicating progress toward their achievement
(Ask about this statement) - provide the beginning and ending dates for the period covered since the project was last reviewed competitively.

11. Re-submission (if applicable)
Response to Critique
Indicate major criticisms in the summary statement and specify changes you are making
Highlight the major substantive issues. Repeating each comment by each reviewer is not necessary if there is congruence and repetition among them