1. BLOOD

2. Components
A. Plasma – thick, sticky, yellowish liquid
1. 90% water
2. 10% salts, proteins, nutrients, waste

3. Red Blood Cells (RBCs)
1. Carry oxygen and carbon dioxide
2. Hemoglobin – protein that binds oxygen and carbon dioxide
a. Also carries iron – makes blood red
3. No nucleus or organelles
a. cannot replicate/undergo mitosis

4. C. White Blood Cells (WBCs - Leukocytes) 1. Fight disease 2
C. White Blood Cells (WBCs - Leukocytes) 1. Fight disease 2. Move in and out of bloodstream – gather at sites of infection 3. Engulf foreign bodies (bacteria, viruses, etc.)by phagocytosis 4. Make antibodies – respond to specific diseases

5. Types of WBCs Monocytes and Macrophages– phagocytes
Eosinophils – parasitic infections and allergic reactions
Basophils – histamine response
Lymphocytes – B cells and T cells
Neutrophils – bacterial and fungal infections

6. Platelets – cell fragments
1. Responsible for clotting – clump at wound

7. A. Anemia – conditions in which RBCs don’t carry enough oxygen
Disorders
A. Anemia – conditions in which RBCs don’t carry enough oxygen
1. Iron deficiency
2. Aplastic – body doesn’t make enough RBCs
3. Hemolytic – RBCs broken apart
4. Sickle-cell – hemoglobin gene mutation

8. Lymphoma and leukemia
1. WBCs become cancerous

9. C. Hemophilia – genetic disorder – don’t make certain proteins that help blood clot

10. Blood Types
A. Can carry antigens on your RBCs and antibodies in your plasma

11. B. Transfusion of wrong blood type causes an immune response that results in agglutination (antibodies in plasma will attach to antigens on donated RBCs and cause clumping)
Donor Type A B AB O
Recipient Type

12. C. Rh factor – other antigens that may or may not be present (+ or -) 1. Pregnancy – first pregnancy of Rh- mom with Rh+ baby - > mom creates antibodies to Rh. Second pregnancy, if baby is Rh+, antibodies from mom can destroy fetal RBCs