1. The Nephron
Unit 12: Assignment 1

2. Learning Outcomes To understand the process of ultrafiltration
To begin to understand the process of Selective Reabsorption
To know some signs of dehydration

4. The Nephron

5. Ultrafiltration Filtering at a molecular level Glomerulus
Bowman’s Capsule

6. Ultrafiltration
Filtration of the blood to move substances into the nephron
Filtered based on size
Any molecule with a relative molecular mass of more than 69,000 will not be filtered.

7. Collagen Sodium Immunoglobulin Water Haemoglobin Urea Glucose Glycine
Task: Molecule Size
List these atoms/molecules in order of size and decide which will / will not be filtered at the glomerulus:
Collagen Sodium Immunoglobulin Water Haemoglobin Urea Glucose Glycine

8. Molecule Size and Filtration
The following passes through from the blood to the nephron:
Water
Salts (Na,K,Cl)
Glucose
Urea
Small Amino Acids

9. Selective Reabsorption
Ultrafiltration is non selective (i.e. any molecule small enough is filtered) Some substances are needed in the body so must stay in the bloodstream These molecules are reabsorbed from the proximal convoluted tubule into the blood.

10. Secretion / Absorption
Secretion: Substances moving from blood to nephron. Absorption: Substances moving from nephron to blood.

11. Which are needed in the blood?
Fill in the table:
Substances needed in the blood:
Substances to be excreted in the urine:

12. Which are needed in the blood?
Fill in the table:
Substances needed in the blood:
Substances to be excreted in the urine:
Glucose
Urea
Amino Acids
Water
Salts

13. Summarise the processes happening in the nephron:

14. Dehydration:
Definition?

15. Dehydration:
List the symptoms of dehydration:

16. 8 Common signs of dehydration
Take notes, I’ll test you afterwards!!

17. Class Work Task:
Complete your labelled Nephron diagram for your pass criteria.
Use text books to research and make notes on:
Osmoregulation
Dehydration
3) Begin producing a booklet on Dehydration