1. Equipoise ”Balance of forces or interests”

2. Clinical equipoise or the principle of equipoise provides the ethical basis for medical research that involves assigning patients to different treatment arms of a clinical trial. The term was first used by Benjamin Freedman in 1987.
Freedman et al NEJM 1987

3. How is equipoise defined or interpreted
How is equipoise defined or interpreted? Experiences of the individual physician or defined by the level of uncertainty that exists in the medical community
Freedman et al NEJM 1987

4. REVIVE-IT RCT OMM versus LVAD
Ambulatory, non-inotrope dependent cohort with advanced heart failure
Receiving maximal medical therapy
NYHA class III limitations
LVEF < 35%
6 MWT distance < 300m
Peak VO2 between % of predicted with an absolute value < 16 ml/Kg/min for men and < 14 ml/Kg/min for women

5. Speakers
Ileana Pina, MD MPH
Andrew Boyle, MD
Larry Allen, MD