1. The Role of MRD in Hematologic Malignancies

2. Educational Objectives

3. Minimal Residual Disease

4. Flow Cytometry

5. MRD Sensitivity Using Flow Cytometry By Disease State

6. Genetic Methods for MRD Quantification

7. Allele-Specific Oligonucleotide (ASO)-PCR

8. MRD Methods – Next Generation Sequencing

9. MRD Methods – Next Generation Sequencing

10. ASO-PCR vs NGS

12. Comparison of MRD Assessment Approaches

13. Current Role of MRD Assessment in Clinical Care

14. MRD in Acute Lymphoblastic Leukemia Children’s Oncology Group AALL0232

15. COG AALL0232: Outcomes

18. ALL: Outcomes by Quantitative MRD Ranges

19. MRD Following HCT in ALL

21. Post Transplant MRD in CLL

23. MRD and Outcomes in MM

24. MRD in Non-Hodgkin Lymphoma

27. Summary of MRD in Lymphoid Malignancies

28. Future Perspectives in MRD

29. Abbreviations

30. References

31. References (cont)

32. References (cont)