1. Merkel Cell Carcinoma: What Do Clinicians Need to Know?

3. Merkel Cell Carcinoma (MCC)

4. MCC Is Easy to Miss

5. Diagnosis of MCC Requires Biopsy and Pathology

6. Risk Factors for MCC

7. Clinical Characteristics of MCC

8. Presenting Sites in MCC

9. Pathologic Staging of Lymph Nodes

10. AJCC Staging System for MCC

11. Initial Management of MCC

12. How Does MCC Arise?

13. The Perfect Storm

14. Mechanisms for Development of MCC

15. Antibodies to MCPyV Oncoprotein Marker for MCC Recurrence

16. The Role of T Cells in MCC

17. PD-1/PD-L1 Pathway Blockade in MCC

18. Pembrolizumab: Anti-PD-1 Antibody in MCC

19. Most Responses Persist

20. Progression-Free Survival (PFS) in MCC

21. Avelumab: Anti-PD-L1 Antibody in MCC

22. Most Responses Persist

23. PFS in MCC

24. Concluding Remarks

25. Abbreviations

26. Abbreviations (cont)