1. Avanafil for the Treatment of Erectile Dysfunction: A Multicenter, Randomized, Double- Blind Study in Men With Diabetes Mellitus 
Irwin Goldstein, MD, LeRoy A. Jones, MD, Laurence H. Belkoff, DO, Gary S. Karlin, MD, Charles H. Bowden, MD, Craig A. Peterson, MS, Brenda A. Trask, BS, Wesley W. Day, PhD 
Mayo Clinic Proceedings 
Volume 87, Issue 9, Pages (September 2012)
DOI: /j.mayocp
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2. FIGURE 1
Patient disposition in the study. In total, 1378 patients were enrolled in the study and 390 were assigned randomly to treatment. Of the 390 randomized patients, 333 completed the study and 57 discontinued participation. tx = treatment.
Mayo Clinic Proceedings  , DOI: ( /j.mayocp )
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3. FIGURE 2
Effect of treatment between baseline and the treatment period on Sexual Encounter Profile (SEP) 3 (intent-to-treat [ITT] population) (A) and SEP 2 (ITT population) (B) and from baseline to the end of treatment on International Index of Erectile Function erectile function (IIEF-EF) domain score (ITT population) (C), normalization of IIEF-EF domain score (≥26) (ITT population) (D), and percentage of successful sexual attempts (SEP 3) over time after dosing (ITT last observation carried forward population) (E). *P<.001 vs baseline; †P=.009 vs baseline; ‡P=.007 vs baseline.
Mayo Clinic Proceedings  , DOI: ( /j.mayocp )
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