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Volume 147, Issue 1, (September 2011)

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Presentation on theme: "Volume 147, Issue 1, (September 2011)"— Presentation transcript:

1 Volume 147, Issue 1, (September 2011)
Cancer's Epigenome  Cell  Volume 147, Issue 1, (September 2011) DOI: /j.cell Copyright © Terms and Conditions

2 A multidimensional scaling of methylation for selected CpGs in cancer, showing the distribution of normal tissues (left) and cancer (right). A few cancer samples fall within the normal range but do not define a tight distribution themselves. Dotted lines indicate the typical variation for normal tissues. Image courtesy of K.D. Hansen and W. Timp. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

3 Genome-wide visualization of somatic mutation targets in non-Hodgkin lymphoma from Morin et al. (2011). Purple circles mark genes mutated in more than one case, with their diameters proportional to the number of cases with single-nucleotide variants observed. Image courtesy of R. Morin. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

4 Histology image of a hepatitis C-associated liver cancer case with an ARID2 mutation. Image courtesy of M. Torbenson. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

5 The confocal image in the Sputnik satellite shows a cell overexpressing satellite DNA and with abnormally amplified centrosomes (red). At center is a mathematical deconvolution of the confocal image to resolve the tubulin fibers (green) and the individual chromosomes (blue). Image courtesy of Q. Zhu, J. Fitzpatrick, and J. Simon. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions


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