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Metastatic Breast cancer
Case Report
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General information Name: WU ChunHong Age: 40y Sex: Female
Date of admission: February 9th,2011 Date of discharge: April 23th,2011
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Chief complaint She got hypoesthesia of lower limbs and inability to walk for more than a month
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History of present illness
The patient felt pain on the back by no obvious incentives in June 2010 The pain was tingling, especially in night-time The patient took orally traditional Chinese medicine , but had not tangible effects
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Past, Personal & Family History
No hepatitis, hypertension, or diabetes No smoking, alcohol or drug abuse No inherited diseases No history of drug allergy Normal menstruation
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Clinical findings The left breast presented with diffused erythema and edema , induration about size of 3.0cm*3.0cm
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Ultrasound examination
a 3 cm left breast mass and a normal right breast
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Thoracic MRI examination
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Thoracic MRI examination
Enhanced MRI High-density mass was shown on the seventh thoracic, and bone destruction also had been found.
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Laboratory examination
1.Hepatic functions ALT 40 U/L AST 20 U/L TB Normal 3.Tumor markers CA Normal 2. Blood routine test Hb g/L RBC 4.54×1012 /L WBC 6.1×109 /L PLT ×109 / L
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puncture biopsy She received ultrasound guided breast core needle puncture biopsy Puncture tissue pathology :The left breast invasive ductal carcinoma
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Breast cancer with bone metastasis
Primary diagnosis Breast cancer with bone metastasis
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Treatment On February 11, 2011 in orthopedic department,
The Patient received "the seventh thoracic tumor resection and pedicle screw fixation"
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Histological examination
Seventh thoracic tumors was identified as metastatic carcinoma, and the immunohistochemistry results showed the possibility of breast cancer bone metastasis was very large
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IMMUNOHISTOCHEMICAL results
ER++ PR++ CerbB2- CK20- EMA++,Ckpan+++,CK5/6-
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Treatment The patient recovered well , and then transferred into our department Chemotherapy two times before operation: February 23 ,2011 March 20 ,2011 The chemotherapy plan was TEC
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Treatment The lesions area of left breast showed no reduction
After the chemotherapy The lesions area of left breast showed no reduction
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Treatment Modified radical mastectomy on march 31,2011 On the same day
Bilateral oophorectomy On the same day
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Histological examination
The left breast invasive ductal carcinoma The basal resection margin of tumor was close to the surrounding normal tissue The axillary lymph nodes metastasis (13/15)
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Immunohistochemical ER++ PR++ CerbB2- E-cad+++,Ki6750%+,P53+,Ck5/6-
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Treatment After operation, the patient continued to receive chemotherapy and radiotherapy.
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Thank you
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