1. OIE Reference Laboratories transboundary animal disease control
The contribution of
OIE Reference Laboratories to
transboundary animal disease control
Gideon Brückner and Keith Hamilton
OIE Headquarters, Paris

2. World Organisation for Animal Health (OIE)
An intergovernmental organisation, founded in 1924
174 Members (In June 2009)
Headquarters in Paris, France
5 Regional offices
5 Regional sub offices 52 13 13 29 51 29

3. Priorities of the IVth Plan (2006-2010)
Consolidation of 3 missions from the former Strategic Plan
To ensure transparency in the global animal disease situation
Publishing scientific based standards, especially with reference to the WTO
Publishing guidelines for the prevention, control and eradication of animal diseases, including zoonosis; acknowledgement of Members health status 3

4. Animal diseases are a serious threat
Animal health and welfare
Public health - zoonoses

5. Animal diseases are a serious threat
Livelihoods
Economics:
productivity,
trade,
market access
Food security – nutrition
(inc. non zoonotic

6. Vulnerability to animal diseases
Rising global population needs food
Globalisation
Climate change
Ecological changes
Emerging infectious diseases

7. Zoonotic potential 60% of human pathogens are zoonotic
75% of emerging diseases are zoonotic
80% of agents having a potential bioterrorist use are zoonotic pathogens

8. Pathogen spread
Pathogens are transported around the world faster than the average incubation time of most epizootics
There is no place in the world from which we are remote and no one from whom we are disconnected 8

9. Factors of emergence and re-emergence of animal diseases and zoonosis
Dr Lonnie King, CDC, Atlanta 9

10. The concept of “One World-One Health” (OWOH)
A global strategy for preventing and managing risks at the human-animal interface
Cooperation is important particularly for predictions, prevention and response

11. Veterinary services are a global public good
poverty alleviation
protecting animal health
food security
protecting public health
market access
protecting animal welfare
food safety

12. Expertise and capacity underpin the ability to prevent, detect and control important animal diseases, including zoonoses

13. Global network of OIE expertise
OIE Reference Laboratories – expertise in surveillance and control of a named disease
OIE Collaborating Centres – expertise in a specific designated sphere of competence e.g. epidemiology, emerging avian diseases, zoonoses, veterinary medicinal products .

14. Mandate of OIE Ref Laboratories
to function as a centre of expertise and standardisation for a designated disease(s) or topics;
to store and distribute to national laboratories biological reference products and any other reagents used in the diagnosis and control of the designated disease(s) or topics;
to develop new procedures for diagnosis and control of the designated disease(s) or topics;
to gather, process, analyse and disseminate epizootiological data relevant to their speciality;
to place expert consultants at the disposal of the OIE.

15. OIE Ref Laboratories may also contribute to:
provision of scientific and technical training for personnel from Member Countries;
provision of diagnostic testing facilities to Member Countries:
organisation of scientific meetings on behalf of the OIE;
coordination of scientific and technical studies in collaboration with other laboratories or organisations;
publication and dissemination of any information in their sphere of competence

16. Reference Laboratories Collaborating Centres
Summary of information on OIE Reference Laboratories and Collaborating Centres in 2009
Reference Laboratories
Collaborating Centres
Total
Number
187 35
222
Countries 36 20 41
Diseases/ Topics
100 33
133
Experts
161
196

17. The reality of the transboundary animal disease situation
More than 100 of the 174 OIE Members are from developing or in-transition countries
More than 70% of OIE listed diseases occur in these countries
Most of the most important TAD’s occur in these countries
Most of the OIE RL’s or CC’s are not situated in these countries
The mandate of OIE RL’s and OIE CC’s thus stretch way beyond their own national borders

20. Percentage of Laboratories carrying out these activities
General activities of OIE Reference Laboratories
Percentage of Laboratories carrying out these activities 1
Test(s) in use/or available for the specified disease
100% 2
Production and distribution of diagnostic reagents
86%
Specific OIE activities 3
International harmonisation/standardisation of methods
68% 4
Preparation and supply of international reference standards
59% 5
Research and development of new procedures
88% 6
Collection, analysis and dissemination of epizootiological data 7
Provision of consultant expertise
66% 8
Provision of scientific and technical training 9
Provision of diagnostic testing facilities
52% 10
Organisation of international scientific meetings
37% 11
Participation in international scientific collaborative studies 12
Presentations and publications
83%

21. Percentage of Collaborating Centres carrying out these activities
General activities of OIE Collaborating Centres
Percentage of Collaborating Centres carrying out these activities 1
Activities as a centre of research, expertise, standardisation and dissemination of techniques
92% 2
Proposal or development of any procedure that will facilitate harmonisation of international regulations applicable to the surveillance and control of animal diseases, food safety or animal welfare
71% 3
Placement of expert consultants at the disposal of the OIE
75%
Specific OIE activities 4
Provision of scientific and technical training within to personnel from OIE Member Countries and Territories
79% 5
Organisation of scientific meetings on behalf of the OIE
46% 6
Coordination of scientific and technical studies in collaboration with other laboratories or organisations 7
Publication and dissemination of information

22. Early detection is essential for rapid response

23. Transparency of the disease situation
OIE Reference Laboratories provide a global disease surveillance network in which we can have confidence

24. International Standards
Surveillance
Safe trade in animals and products
Diagnostic tests and vaccines
Veterinary Services

25. International Cooperation

26. Networks
Strengthen links within animal health network and with human health networks
Share material and information
Develop better diagnostics

27. The OIE - a global partner in the promotion of animal health and food security
GF-TADS
FAO/OIE Crisis Management
Center

28. OIE Laboratory Twinning - sustainable capacity building

30. To extend the network of expertise
Priority regions and diseases
Global geographical coverage of expertise, focused on developing and transition countries
Better global disease surveillance
Greater access for more countries to high quality diagnostics and expertise for early detection and rapid response

31. Scope Compliance with OIE International Standards
Ultimate aim to become an OIE Reference Laboratory or Collaborating Centre
Mutually beneficial and collaborative research opportunities

32. Twinning projects active and underway
Italy - Russia; avian influenza and Newcastle disease
USA - Brazil; avian influenza and Newcastle disease
Germany - Egypt; avian influenza and Newcastle disease
Italy - Cuba; avian influenza and Newcastle disease
UK - South Africa; avian influenza and Newcastle disease
UK - Botswana; avian influenza and Newcastle disease
UK - China; CSF and rabies
Italy - Eritrea; brucellosis
UK - Turkey; brucellosis
Italy - Cuba; epidemiology
Italy - Botswana; CBPP
UK - Morocco; bluetongue and African horse sickness
Germany - Turkey; rabies

33. Future One world one health New challenges
Extending global network of expertise
Technological revolution
Public private partnerships

34. No biosecurity measures, No food safety / food security,
Without the support of OIE Reference Laboratories in the control and diagnosis of transboundary diseases…
No early detection,
No rapid response,
No biosecurity measures,
No food safety / food security,
No reliability of export certification
No scientific basis for international animal health standards

35. 12 rue de Prony, 75017 Paris, France - www.oie.int – oie@oie.int
Organisation mondiale de la santé animale
World Organisation for Animal Health
Organización Mundial de Sanidad Animal
12 rue de Prony, Paris, France - –