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Enzymes
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What Are Enzymes? Most enzymes are Proteins
Act as Catalyst to accelerates a reaction Not permanently changed in the process
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Enzymes Are specific for what they will catalyze Are Reusable
End in –ase -Sucrase -Lactase -peroxidase
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How do enzymes Work? Enzymes work by weakening bonds which lowers activation energy
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Enzymes Without Enzyme With Enzyme Free Energy
Progress of the reaction Reactants Products Free energy of activation
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Enzyme-Substrate Complex
The enzyme acts on the substrate Enzyme Joins Substrate
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Active Site A restricted region of an enzyme molecule which binds to the substrate. Active Site Enzyme Substrate
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Induced Fit A change in the shape of an enzyme’s active site
Induced by the substrate
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Induced Fit A change in the configuration of an enzyme’s active site
substrate induced fit
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What Affects Enzyme Activity?
Environmental conditions can affect enzyme activity.
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Environmental Conditions
Extreme Temperatures are the most deleterious - high temps may denature (unfold) the enzyme. pH (most like pH near neutral) Ionic concentration (salt ions)
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