1. Modeling selection for lactase persistence in African pastoralist and agro-pastoralist societies
Methods: sdrawkcab EMED
Model Asumptions:
Selection on Pastoralists was greater than on the Agro-pastoralists.
Longer selection period in the Agro-pastoralists.
Conlusion: Weak selection pressure could explain the lactase persistence genotype frequencies observed in two African populations.
Pastoralists
Agro-pastoralists
Pop. 1
Starting conditions p0
0.276 q0
0.724
Selection
WAA
1.000
WAB
0.999
WBB
0.990 N
2,000
Starting conditions p0
0.373 q0
0.627
Selection
WAA
1.000
WAB
0.999
WBB
0.995 N
2,000
Approximate time of mutation= , st.dev=1717, Nsim = 20
Approximate time of mutation= -6125, st. dev=2273, Nsim = 20
Marsha Timmerman, Joyce Cadwallader, Srebrenka Robic, Bill Bromer