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Inhaled Drugs UABD – Nebulized Liquid
MDI – Pressurized Meter Dose Inhaler Canister DPI – Dry Powder Inhaler
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Classifications by Mechanism
I. Bronchodilators – Reduces bronchial smooth muscle constriction II. Corticosteroids – Reduce bronchial wall inflammation (swelling) III. Mucoactive Agents – has an effect on mucus IV. Antimicrobial – kills microorganisms V. Other
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I. Bronchodilators Rescue Drug A. Short Acting - B. Long Acting -
1) Beta Agonists: Albuterol 2.5 mg Xopenex 1.25 mg 2) Anti Cholinergic: Atrovent (Ipratropium Bromide) B. Long Acting - Serevent (in Advair) Spiriva Rescue Drug
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Short Acting Beta Agonists (beta-2)
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II. Steroids Controller Flovent (in Advair) Pulmicort (MDI or UABD)
Aerobid Qvar Controller Must use as directed may take several doses/days to have therapeutic effect!
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Most come in MDI / DPI
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III. Mucoactive Agents Normal saline – is the carrier in UABD treatments (MDI version doesn’t have) Acetylcystine – Mucomyst 10%-20% solutions – irritating and smells! (give with a bronchodilator NaHCO3- (Bicarbonate solution) Pulmozyme – expensive $$$
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IV. Antimicrobials Pentamidine – Pneumocystis
Tobi (Tobramycin) G- bacteria Colystin – bacteria Ribrivirin
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V. Others Chromolyn Sodium – allergy drug Lidocaine – numbing medicine
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Da rules: Don’t give drugs in the exact same class together: examples:
Pulmicort & Flovent (both steroids) Xopenex and Albuterol (both short acting beta agonists)
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