1. Absorption, Distribution, Metabolism and Elimination: Part I
Joseph Graziano, Ph.D.

9. Major Routes of Drug Administration
Route of Administration
Intramuscular:
Intravenous:
Absorption Pattern
Prompt from aqueous solutions, but slow and sustained from repository forms
Immediate effects,
since absorption is
circumvented

11. Major Routes of Drug Administration
Route of Administration
Oral Ingestion:
Subcutaneous:
Absorption Pattern
Variable; depends on many factors
Prompt from aqueous solutions, but slow and sustained from repository forms

13. Other Routes of Administration
Transdermal patch
Inhalation
Intra-arterial
Intrathecal
Topical: ocular, dermal, intranasal, intravaginal routes all lead to some systemic absorption