1. Data Acquisition for Sleep Architecture Study
Andrew Myers
Ross Fuller
Advisor: Dr. John Cohen

2. Objectives Sleep Study Data Acquisition Conversion of pH data
EEG, EMG, EOG, EKG, pH, Respiratory Rate, Oxygen Saturation
Conversion of pH data
Conversion from hexadecimal to decimal
Event recognition (pH < 4)
Import data into database

3. The Sleep Study
The effects of fundoplication on subjects experiencing sleep disruption due to nocturnal gastroesophageal reflux disorder (GERD)
Conducted in a clinical setting at the Vanderbilt Medical Center’s General Clinical Research Center

4. GERD is a common disorder...
40% of Americans suffer monthly.
7% of Americans suffer daily.
25% of Americans take an antacid >2x/month
It is the most common acid-related disorder.
It is becoming more common as the population ages.

5. What is not known?
The exact relationship between reflux events and sleep stage in normal volunteers and GERD patients.
How fundoplication affects objective sleep patterns in patients with GERD.

6. Fundoplication

7. GCRC Utilization 2 Nights per Subject 21 Subjects
Single Occupancy in a Double Room
Meals, Medications
Sleep tech responsibilities if CRC desires

8. Procedure Admit to CRC Perform pregnancy test
Perform Esophageal manometry & place pH probe at GERD Center
~10pm Set up EEG Equipment
After 8hrs of sleep, remove EEG Equipment
Remove pH probe

9. Analysis Esophageal pH data downloaded
Sleep data interpreted by neurologist (blinded)
Questionnaire, pH, sleep data integrated on database

10. Work Completed (1)
"05 01C3 Samples" "3F433D413F413D413D423D D413E453F443F413E453F463E433D413D433D413E423D413E463D423E413C443D”
Visual Basic code converting this to decimal
Output file displays events (pH<4) at the time of occurrence
Synchronized with EEG machine providing sleep comparison

11. Work Completed (2) Successful practice run on overnight patient
Proper EEG, EMG, EOG, EKG sensitivity and filter settings
Neurologist can determine stage with 5 second accuracy
Event recognition of pH code

12. Future Work Designsafe Analysis
Start actual study (first patient last Friday)
Determine if collected data is adequate as deemed by the advisor (Dr. John Cohen) and the neurologist
Direct import of data into the database