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Volume 32, Issue 2, Pages (April 2014)

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Presentation on theme: "Volume 32, Issue 2, Pages (April 2014)"— Presentation transcript:

1 Volume 32, Issue 2, Pages 227-235 (April 2014)
Clinical Presentations of Severe Cutaneous Drug Reactions in HIV-Infected Africans  Rannakoe J. Lehloenya, BSc, MBChB, FCDerm(SA), Mahlatse Kgokolo, BPharm, MBChB, MMed, FCDerm(SA)  Dermatologic Clinics  Volume 32, Issue 2, Pages (April 2014) DOI: /j.det Copyright © 2014 Elsevier Inc. Terms and Conditions

2 Fig. 1 Morbilliform eruption without systemic features in an HIV-infected woman. Dermatologic Clinics  , DOI: ( /j.det ) Copyright © 2014 Elsevier Inc. Terms and Conditions

3 Fig. 2 Erythema, facial edema, and exfoliation in a patient with DRESS syndrome. Dermatologic Clinics  , DOI: ( /j.det ) Copyright © 2014 Elsevier Inc. Terms and Conditions

4 Fig. 3 TEN in an HIV-infected woman showing a positive Nikolsky sign and small areas of early epidermal denudation. Dermatologic Clinics  , DOI: ( /j.det ) Copyright © 2014 Elsevier Inc. Terms and Conditions

5 Fig. 4 (A) Scarring, hyperpigmentation, and milia after SJS. (B) Scarring of the labia minora after genital involvement in SJS. (C) Pterygium of the nail in a patient with SJS. Dermatologic Clinics  , DOI: ( /j.det ) Copyright © 2014 Elsevier Inc. Terms and Conditions

6 Fig. 5 Lichenoid drug eruption with depigmentation in an HIV-infected man on treatment of a second episode of tuberculosis with Rifafour, a combination drug of rifampicin, isoniazid, pyrazinamide, and ethambutol. The rash initially developed during the first course of tuberculosis treatment and resulted in areas of depigmentation and hyperpigmentation. This picture shows recurrence with violaceous patches within the depigmented areas from the first episode. Dermatologic Clinics  , DOI: ( /j.det ) Copyright © 2014 Elsevier Inc. Terms and Conditions

7 Fig. 6 (A) Annular erythema of the V of the neck and (B) tender indurated palmar erythema in a patient recently started on Odimune, a once-daily combination antiretroviral drug comprising efavirenz, tenofovir, and emtricitabine. Dermatologic Clinics  , DOI: ( /j.det ) Copyright © 2014 Elsevier Inc. Terms and Conditions

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