1. Cerebral palsy profile (cp-pro)
Jacob Kean, PhD

2. We need good measures
Children with CP represent a very diverse population
Measures must cover the full range of abilities and problems
Assessment can be burdensome
Brevity is important for children with CP
Assessing children
Physical and cognitive limitations
Time constraints in busy practice environments

3. Cerebral palsy profile (CP-PRO)
Developed at Boston University and Shriners Hospital for Children
Four item banks
Activity
Global Health
Lower Extremity Function
Upper Extremity Function
Parent-reported outcome measures

4. T-score metric
0-100, M=50, SD=10

5. Key Considerations When Using CAT
Not all items answered by each person
Person’s responses to previous items determines what item is presented next
Scores across persons can be compared despite administration of different items
Clients answer different items on repeated administration of the same CAT
Filters
Clients will never answer items that are not applicable
Walking items for those who only use chairs
Gender specific items

6. Short Forms (SF) Needed if CAT is not feasible or desired
Select 8-10 items from the calibrated item bank
Cover appropriate range of function: enough items at upper, middle and lower parts of the scale
Select items that can discriminate different abilities levels
Ensure that items assess important abilities
Can link scores from CAT-administered tests

7. Impact: cost, sample size, study duration
Comparing active treatment and placebo groups in a clinical trial
Measure 1 (CTT; More Measurement Error)
Measure 2 (IRT; Less Measurement Error)
α=0.05, β=0.20, SD=17.2, Δ=5
α=0.05, β=0.20, SD=6.7, Δ=5
Sample Size = 189
Sample Size = 29
$1500/participant = $283,500
$1500/participant = $43,500
10 participants/month = 19 months
10 participants/month = 3 months

8. Integration with Mycp and ehr
Working to develop web-based administrations using the MyCP platform
CAT or SF
Web-based system could write t-scores to EHR
SF could be licensed to CPRN sites or others

9. Questions