1. 12 A Cell Nucleus Chapter 12: Chromosome 12 144,475 149 aa ABCC9
DNA Sequence
Chromosome
144,475
Name of Protein 12
Name of Gene
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCC9
transcription
Amino acid sequence
mRNA
149 aa
translation
Cytoplasm
A Cell
Nucleus
What does this protein make up or do?
ABC proteins transport various molecules across extra- and intra-cellular membranes
Condition/Disease
Mutations in this gene are associated with cardiomyopathy

2. Description of Chromosome 12
Symptoms and characteristics
. ABC proteins transport various molecules across extra- and intra- cellular membranes
This protein is a member of the MRP subfamily which is involved in multi-drug resistance.
This protein is thought to form ATP- sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle.
Protein structure suggests a role as the drug-binding channel- modulating subunit of the extra- pancreatic ATP-sensitive potassium channels.

3. Who is affected? Anyone, but the following have a higher risk:
Anyone who has sleep deprivation in there family tree
Outlook or quality of life
There are many types of ways to deal or aid sleep deprivation.
Sleeping medication.
Researcher: DS

4. References http://www.genecards.org/cgi- bin/carddisp.pl?gene=ABCC90
References