1. Membrane at Rest Selectively Permeable Channels Ion Concentration Differences Nernst Relationship Ion Pumps

2. Reflex Loop: Sensory-to-Motor

3. Water

4. Phospholipid Bilayer

5. Membrane is Impermeable

6. Channels Allow Ions to Pass

7. Protein Structure

8. Ion Channel

9. Potassium Channel

10. Potassium Channel Pore

11. Channels

21. Ion Concentrations and Nernst Potentials

22. Nernst Relation E = 61.54 mV log 10 [ion] out / [ion] in Lets call it 60 mV

23. Ion Concentrations and Nernst Potentials

24. Ion Transporters

28. Goldman Equation V m = 60 log 10 P k [K o ] + P Na [Na o ] P k [K in ] + P Na [Na in ]

30. Astrocytes Buffer Potassium

31. What two functions do proteins in the neural membrane perform to establish and maintain the resting membrane potential? ON which side of the membrane are sodium ions more abundant? When the membrane is at the potassium equilibrium potential, in which direction (in or out) is there a net movement of potassium ions? There is much greater concentration of potassium ions inside than outside the membrane. Why, then is the resting potential negative? When the brain is deprived of oxygen, the mitochondria within neurons cease producing ATP. What effect would this have on the membrane potential? Why? Questions

32. Next Class Chapter 4 The Action Potential