1. Immunology and the Lynch Syndrome
Henry T. Lynch, Kristen M. Drescher, Albert de la Chapelle 
Gastroenterology 
Volume 134, Issue 4, Pages (April 2008)
DOI: /j.gastro
Copyright © 2008 AGA Institute Terms and Conditions

2. Figure 1
Generation of anti-tumor responses in MSI-H cancer. Mutations in MMR genes induce the expression of novel frameshift peptides by the tumor. Because the patient has not been tolerized to these peptides, a potent immune response to the peptides develops. This resultant immune response helps control tumor growth and spread.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2008 AGA Institute Terms and Conditions