1. Changes in vessel-wall thickness and vessel-wall area in the thoracic aorta
Atorvastatin 20 mg (n=25 lesions)
Atorvastatin 5 mg (n=25 lesions)
p (20 mg vs 5 mg)
Maximal vessel-wall thickness
Baseline (mm)
3.8
3.7 NS
12 months (mm)
3.3
<0.05
Change (%)
-12.0
+1.0
<0.001
p (compared with baseline) -
Vessel-wall area
Baseline (mm2)
135
12 months (mm2)
112
139
-18.0
+4.0 —
Yonemura A et al. J Am Coll Cardiol 2005; 45:

2. Changes in vessel-wall thickness and vessel-wall area in the abdominal aorta
Atorvastatin 20 mg (n=35 lesions)
Atorvastatin 5 mg (n=40 lesions)
p (20 mg vs 5 mg)
Maximal vessel-wall thickness
Baseline (mm)
3.3
3.2 NS
12 months (mm)
Change (%)
-1.0
+5.0
<0.02
p (compared with baseline)
<0.01 —
Vessel-wall area
Baseline (mm2) 85 81
12 months (mm2) 87 89
+3.0
+12.0
<0.05
<0.001
Yonemura A et al. J Am Coll Cardiol 2005; 45: