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Mimosa pudica Protects the Testes Against Cadmium-Induced Inflammation and Oligospermia: Potential Benefits in Treatment of Heavy Metal Toxicity  F.M.

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Presentation on theme: "Mimosa pudica Protects the Testes Against Cadmium-Induced Inflammation and Oligospermia: Potential Benefits in Treatment of Heavy Metal Toxicity  F.M."— Presentation transcript:

1 Mimosa pudica Protects the Testes Against Cadmium-Induced Inflammation and Oligospermia: Potential Benefits in Treatment of Heavy Metal Toxicity  F.M. Onyije, M.C. Nwanze, G.O. Alade, T.O. Alade, O.O. Mgbere, C.K. Okpora  Pathophysiology  DOI: /j.pathophys Copyright © 2018 Elsevier B.V. Terms and Conditions

2 Fig. 1 Structures of selected phytochemicals from M. pudica: Mimosine [1], jasmonic acid [2], 5,7,3′,4′-tetrahydroxy-6-C-[β-D-apiose-(1 → 4)]-β-D-glucopyranosyl flavones [3], 5,7,4′-trihydroxyl-8-C-β-D-glucopyranosyl flavones [4], 4-(24′-methoxy-24′-methyl-1′-oxo-5′-n-propyl-tetracosanyl)-phenol [5], 7′-3′-4′-trihydroxy-3,8-dimethoxyflavone [6], and p-coumaric acid [7]. Source: Muhammad et al. [23]. Pathophysiology DOI: ( /j.pathophys ) Copyright © 2018 Elsevier B.V. Terms and Conditions

3 Fig. 2 Mean Sperm Morphology (%) of Experimental Rats by Treatment Groups. Pathophysiology DOI: ( /j.pathophys ) Copyright © 2018 Elsevier B.V. Terms and Conditions

4 Fig. 3 Comparison of the Sperm Count (×106) of Treatment Groups with Control Group. [Treatment Groups: Group A = Water (Control); Group B  = 0.4 mg CdCl2/ml of water; Group C = 0.4 mgCdCl2/ml of water + 250 mg of M. pudica /kg BW; Group D  = 0.4 mg CdCl2/ml of water + 500 mg of M. pudica/kg BW]. Pathophysiology DOI: ( /j.pathophys ) Copyright © 2018 Elsevier B.V. Terms and Conditions

5 Fig. 4 Photomicrograph of Testis H&E x10: Group A (Control) slide shows normal seminiferous tubules (ST) with spermatogenic cells (Spermatogonia (SG), Leydig cell (LC). Pathophysiology DOI: ( /j.pathophys ) Copyright © 2018 Elsevier B.V. Terms and Conditions


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