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Risk of Serious Infections in Patients with Psoriasis on Biologic Therapies: A Systematic Review and Meta-Analysis  Zenas Z.N. Yiu, Lesley S. Exton, Zarif.

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Presentation on theme: "Risk of Serious Infections in Patients with Psoriasis on Biologic Therapies: A Systematic Review and Meta-Analysis  Zenas Z.N. Yiu, Lesley S. Exton, Zarif."— Presentation transcript:

1 Risk of Serious Infections in Patients with Psoriasis on Biologic Therapies: A Systematic Review and Meta-Analysis  Zenas Z.N. Yiu, Lesley S. Exton, Zarif Jabbar-Lopez, M. Firouz Mohd Mustapa, Eleanor J. Samarasekera, A. David Burden, Ruth Murphy, Caroline M. Owen, Richard Parslew, Vanessa Venning, Darren M. Ashcroft, Christopher E.M. Griffiths, Catherine H. Smith, Richard B. Warren  Journal of Investigative Dermatology  Volume 136, Issue 8, Pages (August 2016) DOI: /j.jid Copyright © 2016 The Authors Terms and Conditions

2 Figure 1 Flow diagram showing the identification of literature in the PRISMA statement format. Journal of Investigative Dermatology  , DOI: ( /j.jid ) Copyright © 2016 The Authors Terms and Conditions

3 Figure 2 Forest plot for dose-independent comparison between biologic therapies and placebo. Serious infection at week 12–16 for adults (randomized controlled trials). CI, confidence interval. Journal of Investigative Dermatology  , DOI: ( /j.jid ) Copyright © 2016 The Authors Terms and Conditions

4 Figure 3 Forest plot for dose-independent comparison between biologic therapies and retinoid therapy/phototherapy. Serious infection in adults (cohort studies). CI, confidence interval; IV, inverse variance; SE, standard error. Journal of Investigative Dermatology  , DOI: ( /j.jid ) Copyright © 2016 The Authors Terms and Conditions


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