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Safety of Proton Pump Inhibitor Exposure
Yu–Xiao Yang, David C. Metz Gastroenterology Volume 139, Issue 4, Pages (October 2010) DOI: /j.gastro Copyright © 2010 AGA Institute Terms and Conditions
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Figure 1 Publications that have examined the side effects of PPIs since the release of omeprazole. *Number of articles was calculated based on a PubMed search and then individually selected based on relevance. The PubMed Search terms were ”proton pump inhibitor” OR ”pantoprazole” OR ”lansoprazole” OR ”omeprazole” OR ”esomeprazole” OR ”rabeprazole” AND safety OR adverse events OR risk AND Humans (MeSH) AND English (lang). Gastroenterology , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions
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Figure 2 Potential pathways through which PPI therapy can decrease bone strength. VBMD, volumetric bone mineral density; PTH, parathyroid hormone. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions
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