1. Anatomy and Physiology & Diseases and Disorders
Endocrine System
Anatomy and Physiology
&
Diseases and Disorders

2. Function Communication Control Hormones – chemical messages
Slower – long lasting
Hormones – chemical messages

4. Responsibilities of Endocrine System

5. Water and Electrolyte Balance
ADH (antidiuretic hormone) – retain fluid
Aldosterone
Na/K ions levels
Na – cause cells to swell / shrink
K – causes toxic substances to build up

6. Growth, Development, and Reproduction
Metabolism (blood sugar)
Insulin – cells take up glucose (storage)
Glucagon – release glucose into blood

7. Growth, Development, and Reproduction
Calcium Regulation:
PTH (parathyroid hormone)– raises blood Ca
Calcitonin – lowers blood Ca

8. Central Nervous System
In conjunction with endocrine system (hypothalamus / pituitary gland)

9. Heart and Kidney Function
ADH
Epinephrine/Norepinephrine – HR/BP

10. Immunity / Stress Response
Glucocorticoids – suppress immune response
Epinephrine/Norepinephrine – fight/flight

11. Problems with the Endocrine System

12. Adrenal Insuffeciency
Underproduction of adrenal corticosteroid hormones
Addison’s Disease
John F. Kennedy

13. Cushing Syndrome
Increase in glucocorticoids
Cortisol

14. Diabetes Type I (juvenile) Untreated Insulin Dependent Diabetic coma
Ketoacidosis

15. Diabetes Type II (adult onset) Gestational
Body does not use insulin properly
Gestational
Pregnancy

16. Growth Hormone Abnormalities
Gigantism
Dwarfism
Pituitary Gland

17. Growth Hormone Abnormalities
Acromegaly

18. Hyperthyroidism
Graves’ Disease
Goiter

19. Hypothyroidism
Hashimoto’s thyroiditis