1. Chronic stress accelerated DSS-induced colitis.
Chronic stress accelerated DSS-induced colitis. (A) Body weight of mice in normal and stress groups before DSS and immobility time of mice after 1 mo stress in TST and FST using an EthoVision XT 11.5 system (n = 10). (B) Representative colon pictures and colon length, colon weight, bleeding score, and body weight (n = 9–10). (C) Representative H&E staining, Ki-67 staining, pathological score, and mean positive Ki-67 staining cells counted in 20 crypts (n = 4–5; *P < 0.05, **P < 0.01, and ***P < 0.001). (Scale bars: H&E stain, 100 μm; Ki-67 stain, 50 μm.)‏
Xinghua Gao et al. PNAS 2018;115:13:E2960-E2969
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