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Characteristics of DNA
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DNA Composition 4 different nukleotides (A, T, C, G)
Each nucleotide comprises of a phosphate, a sugar, and a base The sugar molecule in the DNA is deoxyribose (Ribose in RNA) Uracil is replaced with thymine in RNA
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DNA Composition A & G purines C & T pirimidines
[purines] = [pirimidines] [A] = [T] ; [C] = [G] A/T base pairs contains 2 hydrogen bonds C/G base pairs contains 3 hydrogen bonds
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Structure of DNA Double-stranded helicoidal structure
Strands are in opposite direction and antiparallel to each other Complementary strands are bounded with hydrogen bonds to each other Strands have complementary sequences
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Structure of an Nucleotide Adenosine Mono Phosphate (AMP)
OH HO Phosphate NH2 N Base - H+ OH O CH2 Sugar H 2’ 3’ 4’ 5’ 1’ Nukleotide Nukleoside OH
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Purines Pirimidines Uracil CH3 N O NH Thymine N Adenine NH2 NH2 O N NH
(RNA) CH3 N O NH Thymine (DNA) N Adenine NH2 NH2 O N NH Guanine N O NH2 Cytosine
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Base Pairs Guanine and Cytosine
H O N Guanine - N O H Cytosine + + - - +
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Base Pairs Adenine and Thymine
- + Adenine CH3 N O H + - Thymine
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Base Pairs Adenine and Cytosine
H Cytosine - + N H - + Adenine
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Base Pairs Guanine and Tyhmine
CH3 N O H + - Tyhmine H O N Guanine + -
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