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High Prevalence of Liver Fibrosis Among European Adults With Unknown Liver Disease: A Population-Based Study Llorenç Caballería, Guillem Pera, Ingrid Arteaga, Lluís Rodríguez, Alba Alumà, Rosa Ma Morillas, Napoleón de la Ossa, Alba Díaz, Carmen Expósito, Dolores Miranda, Carmen Sánchez, Rosa Ma Prats, Marta Urquizu, Angels Salgado, Magda Alemany, Alba Martinez, Irfan Majeed, Núria Fabrellas, Isabel Graupera, Ramón Planas, Isabel Ojanguren, Miquel Serra, Pere Torán, Juan Caballería, Pere Ginès Clinical Gastroenterology and Hepatology Volume 16, Issue 7, Pages e5 (July 2018) DOI: /j.cgh Copyright © 2018 AGA Institute Terms and Conditions
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Figure 1 Prevalence and 95% CI of liver stiffness ≥ 6.8 kPa in subjects classified according to several risk factors of liver disease. AST, aspartate aminotransferase. Clinical Gastroenterology and Hepatology , e5DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions
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Figure 2 Comparison of area under the receiver operating characteristic curves for significant liver fibrosis according to a LS measurement ≥ 9.2 kPa, as estimated by transient elastography, FLI, ALT level, NAFLD fibrosis score (NFS), and FIB-4 in the whole population of subjects. Clinical Gastroenterology and Hepatology , e5DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions
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Figure 3 (A) Prevalence of LS ≥ 9.2 kPa according to risk factors for liver fibrosis and FLI values. (B) Proposed algorithm for screening for liver fibrosis in the community. The asterisk (∗) indicates if one of the following risk factors is present: obesity, Type 2 diabetes, hyperlipidemia, arterial hypertension, metabolic syndrome, or alcohol risk consumption. Clinical Gastroenterology and Hepatology , e5DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions
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Supplementary Figure 1 Flow chart of the study.
Clinical Gastroenterology and Hepatology , e5DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions
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Supplementary Figure 2 Distribution of liver stiffness values in the whole population studied. Clinical Gastroenterology and Hepatology , e5DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions
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Supplementary Figure 3 Comparison of the area under the receiver operating characteristic curves for significant liver fibrosis (≥F2) according to liver biopsy and LS measurement, NAFLD fibrosis score (NFS), FIB-4, and ALT levels. Clinical Gastroenterology and Hepatology , e5DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions
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