1. Cancer Stem Cell Therapies in Gastrointestinal Cancers

2. Cancer Stem Cells

3. Cancer Stemness

4. CSC Signaling Pathways

5. CSC Treatment Targets

6. Stemness Mechanisms of Progression/Relapse

7. Targeted Pathway Example: STAT3

8. Demcizumab in Pancreatic Cancer

9. Demcizumab Phase 1B Results

10. Demcizumab Phase 1B Safety Findings

11. ɣ-Secretase Inhibitor in Pancreatic Cancer

12. Napabucasin in Pancreatic Cancer

13. Napabucasin 1b/2 Study Results and Safety

14. Napabucasin Registrational Study

15. Napabucasin in mCRC: Methods and Safety

16. Napabucasin in mCRC: Results

17. CCTG/AGITG CO.23 Trial

18. CanStem303C Trial

19. Clinical Impact and Future Directions

20. Abbreviations

21. Abbreviations (cont)