1. Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity 
J.S. Sutherland, A.G. Loxton, M.C. Haks, D. Kassa, L. Ambrose, J.-S. Lee, L. Ran, D. van Baarle, J. Maertzdorf, R. Howe, H. Mayanja- Kizza, W.H. Boom, B.A. Thiel, A.C. Crampin, W. Hanekom, M.O.C. Ota, H. Dockrell, G. Walzl, S.H.E. Kaufmann, T.H.M. Ottenhoff 
Clinical Microbiology and Infection 
Volume 20, Issue 4, Pages O230-O238 (April 2014)
DOI: /
Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

2. Fig. 1
Differential gene expression values in human immunodeficiency virus (HIV)-negative participants from South Africa (SUN), Stellenbosch University; Malawi (KPS), Karonga Prevention Study; The Gambia (MRC), Medical Research Council Unit. RT-MLPA was performed on ex vivo RNA extracted from tuberculosis cases (TB+) and household or community controls (TB–). Median values are shown. Blue indicates relatively low expression and red indicates relatively high expression. Data were analysed with Mann–Whitney U-test for each site; p-values are indicated; NS, not significant.
Clinical Microbiology and Infection  , O230-O238DOI: ( / )
Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

3. FIG. 2
Differential gene expression values in human immunodeficiency virus (HIV)-positive participants per site and total HIV-negative and HIV-positive participants (all sites grouped). RT-MLPA was performed on ex vivo RNA extracted from tuberculosis cases (TB+) and household or community controls (TB˜). Median values are shown. Blue indicates relatively low expression and red indicates relatively high expression. Data were analysed with Mann-Whitney U-test for each site and for total HIV-negative and HIV-positive participants (all sites combined); p-values are indicated; EHNRI, Ethiopian Health and Nutrition Research Institute; SUN, Stellenbosch University; KPS, Karonga Prevention Study; NS, not significant.1 1 Figure 2 was updated on 13/01/2014, after first online publication 11/11/2013. The values in the EHNRI TB+ and TB– are now correct; previously the values in the TB+ column appeared in the TB– column and vice versa.
Clinical Microbiology and Infection  , O230-O238DOI: ( / )
Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

4. FIG. 3
Reverse transcriptase multiplex ligation-dependent probe amplification was performed on ex vivo RNA extracted from tuberculosis cases (TB+) and household or community controls (TB˜) at four sites in Africa. Data are presented from a total of 141 human immunodeficiency virus (HIV)-negative TB-positive, 195 HIV-negative TB-positive, 74 HIV-positive TB-positive and 120 HIV-positive TB-negative participants. Line indicates median, whiskers indicate 5–95% range, and dots indicate outliers. Data were analysed with the Kruskal-Wallis test followed by Dunn's post-test comparison.
Clinical Microbiology and Infection  , O230-O238DOI: ( / )
Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

5. FIG. 4
Reverse transcriptase multiplex ligation-dependent probe amplification was performed on ex vivo RNA extracted from tuberculosis (TB) cases and tuberculin skin test (TST)-positive household or community controls (HCCs) from four sites in Africa. Data are presented from a total of 99 TB cases and 91 TST-positive HHCs (all human immunodeficiency virus (HIV)-negative). Data were analysed by the use of using receiver operator curves, and sensitivity and specificity are shown for IL7R, FCGRIA, and CD3E. AUC, area under the curve.
Clinical Microbiology and Infection  , O230-O238DOI: ( / )
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