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Volume 73, Issue 6, Pages (June 2018)

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Presentation on theme: "Volume 73, Issue 6, Pages (June 2018)"— Presentation transcript:

1 Volume 73, Issue 6, Pages 859-867 (June 2018)
Long-term Psychological and Quality-of-life Effects of Active Surveillance and Watchful Waiting After Diagnosis of Low-risk Localised Prostate Cancer  Sam J. Egger, Ross J. Calopedos, Dianne L. O’Connell, Suzanne K. Chambers, Henry H. Woo, David P. Smith  European Urology  Volume 73, Issue 6, Pages (June 2018) DOI: /j.eururo Copyright © 2017 European Association of Urology Terms and Conditions

2 Fig. 1 Flow diagram showing patients’ participation and follow-up.
European Urology  , DOI: ( /j.eururo ) Copyright © 2017 European Association of Urology Terms and Conditions

3 Fig. 2 Adjustedb mean differences in 10-yr follow-up psychological outcome scores according to initial treatment. AMD=adjusted mean difference; AS/WW=active surveillance/watchful waiting; PSA=prostate-specific antigen; RP=radical prostatectomy; RT=radiotherapy; HDR=high-dose rate brachytherapy; LDR=low-dose rate brachytherapy; SEIFA=Socio-Economic Indexes for Areas; TURP=transurethral resection of the prostate; ref. = reference. a P-het corresponds to p values for tests of equal AMDs between the three individual initial active treatment groups. b Adjusted for age (<65, 65–69, 70–74, 75–80 yr), education (university or college degree, high school, less than high school), socioeconomic status of place of residence (SEIFA quintiles), place of residence (major city, inner regional, outer regional/remote/very remote), private health insurance (insured, not insured), employment status (working, retired/unemployed, other), married or living with de facto (no, yes), country of birth (Australia, elsewhere), comorbidity score at diagnosis (0, 1, 2+), PSA at diagnosis (ng/ml), Gleason score at diagnosis (≤4, 5, 6), clinical stage at diagnosis (T1a–T1b, T1c–T2a), postdiagnosis TURP and baseline mental component score. European Urology  , DOI: ( /j.eururo ) Copyright © 2017 European Association of Urology Terms and Conditions

4 Fig. 3 Adjustedb mean differences in 10-yr follow-up HRQOL scores according to initial treatment. AMD=adjusted mean difference; AS/WW=active surveillance/watchful waiting; RP=radical prostatectomy; RT=radiotherapy; HDR=high-dose rate brachytherapy; LDR=low-dose rate brachytherapy; HRQOL=health-related quality-of-life; SEIFA=Socio-Economic Indexes for Areas; TURP=transurethral resection of the prostate. a P-het corresponds to p values for tests of equal AMDs between the 3individual initial active treatment groups. b Adjusted for age (<65, 65–69, 70–74, 75–80 yr), education (university or college degree, high school, less than high school), socioeconomic status of place of residence (SEIFA quintiles), place of residence (major city, inner regional, outer regional/remote/very remote), private health insurance (insured, not insured), employment status (working, retired/unemployed, other), married or living with de facto (no, yes), country of birth (Australia, elsewhere), comorbidity score at diagnosis (0, 1, 2+), PSA at diagnosis (ng/ml), Gleason score at diagnosis (≤4, 5, 6), clinical stage at diagnosis (T1a–T1b, T1c–T2a), postdiagnosis TURP, and domain-specific baseline HRQOL score. European Urology  , DOI: ( /j.eururo ) Copyright © 2017 European Association of Urology Terms and Conditions


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