1. Pathology Lab Practical Review

2. You will need to be able to identify and provide characteristics of the following microscope slides:
Autolysis of the liver (cirrhosis)
Tuberculosis (Ghon tubercle)
Chronic gastritis
Dissecting aneurysm
Peptic ulcer
Atherosclerosis
Arteriosclerosis
Lobar pneumonia
Pulmonary emphysema
Lung cancer
Myocardial infarction
Melanoma
Diverticulosis
Thrombus

4. Diverticulosis
Small herniations (pouches) form in the gastrointestinal tract
The mucosa (lining of the intestine) becomes thickened with epithelium cells

7. Aneurysm
Fresh: Point of dissection
Healed: Scar tissue

9. Autolysis of the Liver Disorganized intercellular material
Granular appearance of cytoplasm
Orange-peel look
White spots within the cytoplasm
Fat
Clumping of nuclear material

10. Hint:

12. Atherosclerosis
Foam cells
Made up of lipids
Cholesterol clefts

15. Lung Cancer Large nuclei Nuclear clumping Multiple nuclei
Abnormal organelles
Tar may be present

17. Thrombus Blood clot that occludes vessel
Made up of platelets, clotting factors, red blood cells, white blood cells, fibers

19. Arteriosclerosis Calcium deposits in the tunica media and atheroma
The calcium interrupts the elastic fibers of the media

21. Myocardial Infarction
Cardiac cells have lost their striations
Cytoplasm has shrunk creating space between cells
Nuclei are no longer present
White blood cells have moved into the area

23. Chronic Gastritis
Intestinal metaplasia occurs (parietal cells and chief cells degenerate)
Goblet cells are apparent
White blood cells appear

25. Tuberculosis Ghon tubercle present
Necrosed center (possibly calcified)
Fibrous cap on the tubercle

26. Hint Slide

28. Pneumonia Alveoli are congested with white blood cells
Fluid fills some of the alveoli

30. Emphysema Alveoli are extremely large Some alveoli are broken
No white blood cells present

32. Melanoma Large nuclei Nuclear clumping Multiple nuclei
Abnormal organelles
Occurs in the melanocytes

34. Peptic Ulcer
Erosion of normal tissue
White blood cells present