1. Patients Taking Amoxicillin-Clavulanic Can Become Simultaneously Sensitized to Both Drugs 
María Salas, MD, PhD, Jose Julio Laguna, MD, Inmaculada Doña, MD, PhD, Esther Barrionuevo, MD, PhD, Rubén Fernandez- Santamaría, BSc, Adriana Ariza, PhD, Ezequiel Perez-Inestrosa, PhD, Cristobalina Mayorga, PhD, Tahia Diana Fernández, PhD, María José Torres, MD, PhD 
The Journal of Allergy and Clinical Immunology: In Practice 
Volume 5, Issue 3, Pages e3 (May 2017)
DOI: /j.jaip
Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Figure 1
A, Intradermal (ID) positive results with AX and CLV in the immediate reading from P2. B, Patch positive result with CLV in the delayed reading from P4.
The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e3DOI: ( /j.jaip )
Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Figure 2
A, Bars represent mean and SEM of BAT with different BLs in P1, P2, and P3 and 2 control groups. B, Mean and SEM of BAT with different BLs in P1, P2, and P3 without and with WTM inhibition.
The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e3DOI: ( /j.jaip )
Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4. Figure 3
Immunohistochemical staining in the skin biopsy from P4 obtained during the acute phase. Hematoxylin-eosin (H-E) staining showed a dermic perivascular infiltrate of lymphocytes.
The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e3DOI: ( /j.jaip )
Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5. Figure 4
Percentage of different cell subpopulations and cytokine expression at T1 (acute phase) and T2 (resolution phase). A, Lymphocyte subpopulations. B, Different cytokines, cytotoxic markers, and homing receptors in CD3+ cells. C, Cytotoxic markers and IFN-γ expression in CD56+ cells. D, IL-10 expression in CD4+ cells and regulatory T-cell frequencies.
The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e3DOI: ( /j.jaip )
Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6. Figure 5
A, Bars represent maturation index of DCs with 50 μM of AX (light-gray bars), CLV (dark-gray bars), and AX-CLV (black bars). B, Bars represent proliferation index of CD3+, CD4+, and CD8+ lymphocytes with 50 μM of AX (light-gray bars), CLV (dark-gray bars), and AX-CLV (black bars). Dashed lines represent the cutoff point for considering positive values. LTT, lymphocyte transformation test.
The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e3DOI: ( /j.jaip )
Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

7. Figure 6
Flowchart of the suggested allergological workup to evaluate patients who developed a reaction after AX-CLV administration.
The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e3DOI: ( /j.jaip )
Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

8. Figure E1
Representative strategy of basophil selection and determination of activation of P2. Basophils were selected as CCR3+CD203c+ cells from the lymphocyte population. Activation was measured as the percentage of CD63+ basophils.
The Journal of Allergy and Clinical Immunology: In Practice 2017 5, e3DOI: ( /j.jaip )
Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions