1. The ABCs of Nitric Oxide in the Skin

6. NO Is a Potential Therapeutic Option

8. Antimicrobial Properties of NO

9. Antimicrobial Properties of NO (cont)

10. Cytoprotective Properties

11. Immunomodulatory Effects

12. Pathophysiology of Acne

13. Pathophysiology of Acne

14. Pathophysiology of Acne (cont)

15. Inflammatory Processes in Acne

16. Activation of the NLRP3 Inflammasome

17. Th1 and Th17 Immune Responses in Acne

18. P acnes and Inflammation

19. The NLRP3 Inflammasome and Acne

20. NO in Acne

21. Challenges in the Development of an NO-Based Acne Treatment

22. SB204 Study Design

23. SB204 Efficacy Data

24. SB204 Safety Data

25. Concluding Remarks

26. Abbreviations