1. Large Scale Annotation of Genomic Datasets with Genephony
UFGI
Large Scale Annotation of Genomic Datasets with Genephony
Alberto Riva
University of Florida
© 2007, Alberto Riva
11/21/2018

2. Web-accessible; relies on local database for speed and consistency.
Genephony
Genephony is an interactive, flexible and easy to use system for the manipulation of large genomic datasets.
Handles datasets of hundreds of thousands of elements; automates common annotation operations.
Web-accessible; relies on local database for speed and consistency.
© 2007, Alberto Riva
11/21/2018

3. Dataset creation Example:
“Locate all validated SNPs falling in putative Transcription Factor binding sites in the promoters of all genes in the p14.3 band of chromosome 3.” Will use: positions of transcripts and SNPs, predicted TFBSs from MAPPER.
© 2007, Alberto Riva
11/21/2018

4. Derivation and filtering
© 2007, Alberto Riva
11/21/2018

5. Combining datasets
© 2007, Alberto Riva
11/21/2018

6. Other features under development:
SOAP interface;
Multiple organisms (currently human only);
Reannotation of uploaded files;
Simple data analysis;
Additions to knowledge base: PubMed, protein interactions, public gene expression data, etc…
Prototype available at:
© 2007, Alberto Riva
11/21/2018