1. Adaptation to High Altitude in Sherpas: Association with the Insertion/Deletion Polymorphism in the Angiotensin-Converting Enzyme Gene 
Yunden Droma, MD, PhD, Masayuki Hanaoka, MD, PhD, Buddha Basnyat, MD, Amit Arjyal, MD, Pritam Neupane, MD, Anil Pandit, MD, Dependra Sharma, MD, Michiko Ito, MD, Naoyuki Miwa, MD, Yoshihiko Katsuyama, PhD, Masao Ota, PhD, Keishi Kubo, MD, PhD 
Wilderness & Environmental Medicine 
Volume 19, Issue 1, Pages (March 2008)
DOI: /06-WEME-OR-073.1
Copyright © 2008 Wilderness Medical Society Terms and Conditions

2. Figure
Graph of serum ACE activity according to the ACE I/D polymorphism in Sherpas and non-Sherpas.† The ACE activity in both populations is correlated with the genotypes, being significantly highest in the subjects with DD genotype, intermediate in ID heterozygotes, and lowest in II homozygotes. *P<.001 compared with the II homozygotes. The number of subjects is shown in parentheses. †Non-Sherpas indicates non-Sherpa Nepalese residing in Kathmandu Valley, Nepal.
Wilderness & Environmental Medicine  , 22-29DOI: ( /06-WEME-OR-073.1)
Copyright © 2008 Wilderness Medical Society Terms and Conditions