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Interleukins and Atherosclerosis: A Dysfunctional Family Grows

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Presentation on theme: "Interleukins and Atherosclerosis: A Dysfunctional Family Grows"— Presentation transcript:

1 Interleukins and Atherosclerosis: A Dysfunctional Family Grows
Larry D. Spears, Babak Razani, Clay F. Semenkovich  Cell Metabolism  Volume 18, Issue 5, Pages (November 2013) DOI: /j.cmet Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 Inflammatory Cytokines Promote Atherosclerosis
Macrophages secrete IL-1β (bottom), which is thought to be important in this process, but recent evidence implicates IL-1α (top) through a mechanism involving fatty acid-induced respiratory uncoupling and alterations of calcium flux. Cell Metabolism  , DOI: ( /j.cmet ) Copyright © 2013 Elsevier Inc. Terms and Conditions

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