1. the scientific fight against Alzheimer’s disease
Eric M Reiman, MD ∙ Banner Alzheimer’s Institute & Banner Research
University of Arizona ∙ Arizona State University ∙ Translational Genomics Research Institute
Arizona Alzheimer’s Consortium

2. progress

3. genetics

4. biomarkers

5. Reconceptualization of AD
Sperling et al, Alzheimers Dementia 2011; Langbaum et al, Nature Neurol Rev 2013; Jack et al (in press)

6. trials & tribulations

7. TOO LITTLE TOO LATE?

8. prevention

10. Alzheimer’s Prevention Registry: www.endALZnow.org
Reiman et al, Biomarkers Med 2010; Reiman et al, J Alzheimers Dis 2011;
Langbaum et al, Nature Revs Neurol 2013; Reiman et al, Nature Revs Neurol 2016 & 2017;
Alzheimer’s Prevention Registry:

11. New York Times, with permission

12. Fleisher et al, Lancet Neurol 2012

13. Fleisher et al, Lancet Neurol 2012

14. what’s next

15. hope & help

16. National Institute on Aging
Acknowledgements
National Institute on Aging
P30 AG19610, RF1 AG041705, UF1 AG046150, R01 AG031581
R01 AG (pending), AMP-AD (pending)
State of Arizona
Arizona Alzheimer’s Consortium
Industry
Genentech, Novartis & Avid/Eli Lilly
Foundations
Banner Alzheimer’s Foundation, NOMIS Foundation, Anonymous Organizations, Flinn Foundation,
Forget Me Not Initiative, Geoffrey Beene Foundation, GHR Foundation, Alzheimer’s Association
Colciencias ,
Our colleagues, collaborators, supporters & valued research participants
Richard Caselli, Kewei Chen & our AAC colleagues
Pierre Tariot, Jessica Langbaum, our BAI, API & CAP colleagues, collaborators & advisors
Francisco Lopera & our University of Antioquia & HPTU colleagues
Our Genentech/Roche, Novartis/Amgen & Avid/Eli Lilly colleagues