1. PowerPoint-Organic Topic-10.5
IB Chemistry
Mr. Thomson
International School Eastern Seaboard

2. Nucleophile and nucleophilic substitution
Reagent that forms a chemical bond to its reaction partner (the electrophile) by donating both bonding electrons.
Examples: CN-, OH-, NH3, and H2O
Source: Wikipedia

3. Generic Nucleophilic Substitution
Images from IB Chemistry Course Companion.

4. Syllabus Statement
Describe, using equations, the substitution reactions of halogenoalkanes with sodium hydroxide.

5. Substitution Substitution
Source for Diagram: Chemistry for use with the IB Diploma Programme, by L. Derry, M. Connor and C. Jordan
Source for Diagram: Chemistry for use with the IB Diploma Programme, by L. Derry, M. Connor and C. Jordan

6. CH3CH2Cl + OH-  CH3CH2OH + Cl-
Example Reaction
CH3CH2Cl + OH-  CH3CH2OH + Cl-
Nucleophile: Reactant with a non-bonding lone pair of electrons.
Source for Diagram: Chemistry for use with the IB Diploma Programme, by L. Derry, M. Connor and C. Jordan

7. CH3CH2Cl + OH-  CH3CH2OH + Cl-
Example Reaction
CH3CH2Cl + OH-  CH3CH2OH + Cl-
Nucleophile: Reactant with a non-bonding lone pair of electrons.
Source for Diagram: Chemistry for use with the IB Diploma Programme, by L. Derry, M. Connor and C. Jordan

8. SN2 Primary Halogenoalkane
Source for Diagram: Chemistry for use with the IB Diploma Programme, by L. Derry, M. Connor and C. Jordan

9. Another SN2 Reaction
Images from IB Chemistry Course Companion.

10. SN1 Tertiary Halogenoalkane
Source for Diagram: Chemistry for use with the IB Diploma Programme, by L. Derry, M. Connor and C. Jordan

11. Another SN1 Reaction
Images from IB Chemistry Course Companion.